I have one Domke bag for my Digital 35's and one for my Medium format equipment. If you are a lens and camera junky like myself you have two cameras and 5 or six lenses, 2-3 flashes and all the accessories. I use the Domke bags for storage and to take on location. I usually take 1 Nikon D200 and 2 lenses and 1 645 Mamiya Pro with two lenses and the Nikon flash system to my shoots. This bag carries it all. Now all I need is a good assistant to carry the lighting bags and gear and I will be all set.