This bag holds an amazing amount of gear. Right now a Canon 5D with a 24-105 F4 zoom attached, a 70-200 F4 zoom, three 580 flashes, battery grip, camera-flip for tripod, all cables, CF cards, manuals, flashlights, notecards & pens,other odds and ends. And it's smaller than my vintage Domke bags that I have used for the last 25 years. This is a complete setup (except for tripod) for the theater and dance photography I do. Since I mainly work indoors I do not need weather protection, but I do need quick access in the dark. My only complaint is that the clip ring for the cover strap is at the very bottom of the bag and quite awkward to work.
This is the second Domke bag I have owned--among a half dozen other brands. My first Domke, a larger bag, I have given to my son: these bags only get better with age. No other bag comes close to the utility and smart design of Domke. Last year I made a mistake and bought a Billingham (very expensive)camera bag and was disappointed from the start compared to the Domke I had given away! So I bought another Domke and won't use anything else.