I suspect it would be possible, but it would not be seamless or easy. The main compartment has a zippered fabric separator/cover that you would probably have to cut out with scissors. Then you'd have to purchase foam to fill the cavity and configure to your needs. So, if I understand your question, I would say it is possible, but perhaps not easy. I wonder if Pelican doesn't make another product that is already configured that way?
Thanks a lot for the suggestion.It seems not a great idea to alter it.I have to choose other options.